Born in America, Arona Reiner was raised in Israel on the Galilean Kibbutz Ramat Yochanan. Her talent was recognized at an early age, but because kibbutz policy precluded members from receiving special instruction in anything that would not be directly useful to the settlement, she was largely self-taught. Later she studied at the Art Students League and Parsons School of Design in New York, attended the Institute of Plastic Arts in Bat Yam, Israel, and learned etching at Bezalel Academy. A member of Israel's Artist Union since 1972, she has taught at the Israel Museum Jerusalem and the Jerusalem Workshop for the Arts.

Included in several group shows, Reiner's work also has been exhibited in 10 one-woman shows and is part of several private and corporate collections. Her most recent project, following completiion of the Men of Israel, is a collaborative effort with Israeli artist Uri Lifshitz for the Tel Aviv Museum.